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Baylor College of Medicine’s Human Genome Sequencing Center (HGSC) Receives Best Practices Award from Bio-IT World

Baylor College of Medicine’s Human Genome Sequencing Center (HGSC), in collaboration with DNAnexus, received a Best Practice award this week at the Bio-IT World Conference and Expo. The award for IT Infrastructure and High Performance Computing recognized the organizations’ work on processing genomic data for the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium using Baylor’s Mercury pipeline.

“This is a great achievement to be recognized at Bio-IT World for the work we’ve done with high performance cloud computing. With DNAnexus’ help, we have been able to operate at scale, store immense amounts of data, work with our collaborators and beat short deadlines – all of which would have been prohibitively expensive or extremely challenging to accomplish using local resources,” said Narayanan Veeraraghavan, Lead Programmer Scientist at the Baylor College of Medicine Human Genome Sequencing Center.

“We are honored to be recognized alongside Baylor’s Human Genome Sequencing Center and proud of our contributions to the CHARGE project,” said Richard Daly, CEO of DNAnexus. “The DNAnexus platform offers research and clinical enterprises a proven high-performance computing infrastructure that allows them to focus on the data and provide the ability to share and collaborate in a secure and compliant cloud-based environment.”

The HGSC’s Mercury pipeline identifies mutations from genomic data, setting the stage for determining the significance of these mutations as a cause of serious disease and is used as the core variant-calling pipeline for the CHARGE Consortium. The CHARGE Consortium is aimed at better understanding how human genetics contributes to heart disease and aging. Over the course of a four-week period, approximately 3.3 million core-hours of computational time were used to analyze more than 14,000 genomes, generating 430TB of results and nearly 1PB of data storage hosted by DNAnexus for further analysis. This project represented the largest genomic analysis ever performed in the cloud.

The Best Practices Awards program was established in 2003 by the editors of Bio-IT World to recognize cutting-edge approaches to the use of information technology to advance basic biomedical research, drug discovery, and clinical trials, while providing a blueprint for success with the potential for impact across the industry. A panel of ten invited expert judges joined the editors in reviewing 30 detailed submissions from organizations ranging from large pharmaceutical and biomedical companies to academic centers to startup service providers around the world, selecting winners in five categories as well as two special awards from the judges and the editors.

For more information please visit https://dnanexus.com/usecases-charge.

About DNAnexus

DNAnexus is powering the genomics revolution with an enterprise-level solution that combines cloud computing with advanced bioinformatics. The DNAnexus team is made up of experts in software, computational biology, and genetics who are on a mission to establish DNAnexus at the center of a growing ecosystem of scientific and clinical research, and diagnostic efforts in personalized medicine. For more information please visit https://dnanexus.com.

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